Mechanism of the drug action is that amprolium competes with thiamine in the system of metabolic coccidia enzymes, disrupting metabolism of carbohydrates, necessary for coccidia life cycle.
Amprolium refers to moderately toxic drugs for warm-blooded animals, and has no mutagenic, sensitizing, embryotoxic and teratogenic effects at recommended doses; it does not preclude formation of immunity to coccidiosis.
During oral administration amprolium is practically not absorbed by gastrointestinal tract, exhibiting its anticoccidial effect on mucosa and submucosa membrane. Amprolium is mainly eliminated unchanged - with feces within 3-4 days.