Buparvakvon is highly active against theileria both in the stage of schizonts and piroplasma stage.
Mechanism of buparvakvon action is currently not fully identified. Presumably, it breaks Theileria’s
mechanism of electron transport in mitochondria.
Application of buparvakvon on the level of cellular structures leads to progressive vacuolization in cytoplasm of parasites, which eventually leads to disruption of the outer membrane structure and nuclear membrane of parasites. At the same time buparvakvon does not affect intracellular structures (including mitochondria), where Theileria is parasitized.
During intramuscular administration the drug is retained in tissues for long time. The period for
buparvakvon semi-withdrawal is about 7 days.