Enrofloxacin as a drug component belongs to the fluoroquinolones group. Mechanism of the enrofloxacin action on bacterial cells based on inhibiting apple acid biosynthesis. It causes morphological changes and destruction of pathogenic microorganisms. The drug is characterized by quick absorption and achieving high concentrations in blood serum.
The drug has a broad spectrum of antibacterial action against Gram-positive bacteria (staphylococci, streptococci, Corynebacterium, Clostridium and Listeria), Gram-negative bacteria (E. coli, Salmonella, Klebsiella, Proteus, Yersinia, Haemophilus influenzae bacteria, Pasteurella, actinobacillus, Pseudomonas, Bordetella, Brucella, Campylobacter) and mycoplasmas.
Enrofloxacin is quickly absorbed from the injection site and penetrates into all tissues and organs of the body. Maximum concentration of the drug in blood is achieved through 0.5-1 hour after administration and retains for 4-6 hours, and therapeutic concentration - for 24 hours.
The drug doesn’t undergo biotransformation in the body and is eliminated mainly unchanged with urine and bile.