The drug has a strong antiparasitic effect against larval and adult stages of nematodes of the gastrointestinal tract and lungs, larvae of subcutaneous, nasopharyngeal and gastric gadflies, blood-sucking lice and sarkoptoid mites.
Ivermectin enhances generation of neurotransmitter for inhibition of gamma-aminobutyric acid, which leads to disruption of neurotransmission, paralysis and death of parasites.
The drug is quickly absorbed from injection site and distributed in organs and tissues of animal, ensuring parasiticidal action within 10-14 days.
Ivermectin has low toxicity for warm-blooded animals in recommended doses, has no sensitizing, embryotoxic, teratogenic and mutagenic action. Ivermectin is eliminated with urine and bile in lactating animals and with milk as well.