Albendazole has a wide range of action it causes destruction of eggs and mature stages of trematodes, mature and immature stages of nematodes and cestodes. It breaks energy metabolism, inhibits fumarate reductase activity that leads to disruption of adenosinetrphosphoric acid synthesis in helminthes.
METSALBEN-10%; 20%
Metsalben 10% & 20%” is ready for use granular anthelmintic drugcontaining 10% or 20% albendazole as active ingredient and fillers (lactose, feeding chalk, precipitated chalk, starch and other inert compounds).
The drug by its appearance is granules with light gray color, faint specific odor, well disintegrated in damp fodder.
The drug is available in two-layer hermetically sealed plastic bags by 0.1 to 0.5 kg and in polymer jars by 0.5 to 10.0 kg.
The drug should be stored in the original container in dry, dark place, out of reach of children at the temperature range +5°C to +30°C. Shelf-life of the drug is 3 years from date of manufacture under specified storage conditions.
Metsalben is administered in large and small cattle, pigs and dogs once by group method in mixture with feed without prior starvation diet in the following doses (mg per 1 kg animal weight):
| Animal species and names of helminthoses | 10% Granulate | 20% Granulate |
| In cattle: - dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis; - fascioliasis, paramphistomatosis, moniaziasis, trichocephaliasis |
75 100 | 37,5 50 |
| In ruminants: - dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis; - fascioliasis, moniaziasis |
50 75 | 25 37,5 |
| In pigs: - ascaridosis, trichocephaliasis, esophagostomiasis,strongyloidosis |
75 | 37,5 |
| In dogs: - toxascaridosis, toxocariasis, uncinariosis, taeniosis |
200 | 100 |
If required the drug may be administered repeatedly.
The drug is used for deworming of cattle, sheep, goats, pigs, horses in the
following diseases:
Cattle:
- dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis;
- fascioliasis, paramphistomatosis, moniaziasis, trichocephaliasis.
Ruminants:
- dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis;
- fascioliasis, moniaziasis
Pigs: ascaridosis, trichocephaliasis, esophagostomiasis, strongyloidosis.
Dogs: toxascaridosis, toxocariasis, uncinariosis, taeniosis
No side effects have been observed by using the drug in recommended doses.
SPECIFIC INSTRUCTIONS: Meat of compulsory slaughtered animals and milk obtained prior specified deadline may be used for feed purposes.
Slaughter for meat of cattle and pigs shall be allowed not earlier than 14 days, sheep and goats - 10 days, use of milk obtained from cows for food purposes - after 3 days and milk obtained from sheep and goats - 4 days after the last drug administration.
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IVERMEKTIN-10
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