is an antibiotic from the macrolide group and effective against Gram-positive and some gram-negative bacteria including Streptococcus, Staphylococcus, Corynebacterium, Clostridium, Pasteurella, erysipelothrix, spirochetes, chlamydia, treponema hyodisenteriae and mycoplasma.
During intramuscular injection antibiotic is rapidly distributed throughout the body and reaches maximum concentration in tissue approximately 1 hour after administration. Therapeutic effect of this antibiotic in tissues retains for at least 20 hours. It is eliminated primarily with urine and with milk in lactating animals.
During oral administration this antibiotic is quickly absorbed by gastrointestinal tract and is penetrated through all organs and tissues of the body. The highest level of tylosin is achieved in lungs, liver, kidneys and mammary glands. After single dose of Vetilozin drug therapeutic concentration of this antibiotic is retained in the body within 15-18 hours.
Tylosin is eliminated mainly with bile and in smaller quantities by urine and milk.